TABLE 1.
Density of Cells with Myt1 Nuclear Immunoreactivity in White Matter of Human Controls and MS Lesions
Case | Lesion stage | Lesion cells (mm2) | PPWM cells (mm2) | NWM cells (mm2) |
---|---|---|---|---|
1 | Control | 15 | ||
2 | Control | 101 | ||
3 | Control | 86 | ||
4 | Demyelinated inactive | 101 | 321 | |
5 | Demyelinated inactive | 113 | 284 | |
6 | Demyelinated inactive | 57 | 309 | |
7 | Early active | 193 | 371 | |
8 | Early active | 113 | 365 | |
9 | Early active | 38 | 309 | |
10 | Early remyelination | 536 | n/a |
PPWM, periplaque white matter adjacent to lesions in MS tissues. NWM, normal white matter in non-neurological controls. n/a, samples are each from a biopsy of the lesion area so PPWM tissue is not available.