Fig. 1.

RARβ2 expression is induced by CD2019 in the adult brain. Rats were treated at the time of lesion by i.c.v. with 180 ng/kg CD2019/day for 14 days. (A) RT-PCR analysis of RARβ2 in normal adult rat cerebellum and cerebral cortex. (B) By Western blotting, there is an increase in the amount of RARβ protein detected in the cortex of CD2019-treated rats compared to the other groups. (C) Quantification of RARβ protein in the cortex. Error bars show SEM, asterisks denote significant difference between non-lesioned vehicle-treated animals and other treatments. ⁎P < 0.005, Student's t-test, n = 3 from three different animals for each treatment group.