Fig. 7.

CD2019 induces functional recovery of the forelimb in lesioned animals. Rats were treated at the time of lesion by i.c.v. with 180 ng/kg CD2019/day for 14 days. (A) In a grid and (B) beam test, CD2019-treated lesioned rats showed functional recovery 4 weeks post-lesion in a grid task and 2 weeks post-lesion in a beam task, whereas there was no significant recovery in the vehicle-treated lesioned animals. Error bar shows SEM. Asterisks denote significant difference between the lesioned treated (CD2019 or vehicle) and non-lesioned vehicle-treated group ⁎P < 0.05, Student's t test, n = 6 rats for each treatment group.