Figure 2. Distribution curve of RE_M values of complete MSA.

Panel A: Histogram of the RE_M scores (+ve/background frequency) vs frequency for all positions of MSA of the MFS transporters. The top 30 RE_M positions depicted in the boxed region were selected for further analysis. The inset represents the same data by a line graph. B: The table shows 16 out of the top 30 high RE_M alignment positions where the residue in CaMdr1p matched with the most frequent amino acid at that particular position in a MSA of 342 MFS members. Their predicted location with respect to CaMdr1p is also displayed in the next column.