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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Neuropharmacology. 2008 Aug 22;56(1):47–55. doi: 10.1016/j.neuropharm.2008.08.015

Figure 6. The presynaptic protein neurogranin is a target of PKC in pro- and anti-manic animal models.

Figure 6

(A) Phosphorylation of neurogranin of prefrontal cortex from mania related animal models.

Western-blot analysis of phosphorylated and non-phosphorylated neurogranin levels in crude homogenates from the frontal cortex of animals undergoing sustained treatment with amphetamine (AMPH), sleep deprivation (SD), imipramine (IMI), and lithium (Li).

(B) Lack of effect on total neurogranin levels in the frontal cortex in all animal models.

For all experimental groups, N=6-8, Student’s t-test, *p<0.05. Data are presented as mean±SE.

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