Figure 7. Phosphorylation of NMDA receptor NR1S896 at PKC site in mania-associated animal models.
Total protein samples from the prefrontal cortex of amphetamine (AMPH)-, imipramine (IMI)-, or lithium (Li)- treated animals or sleep-deprived (SD) animals were subjected to Western blot analysis with anti-phospho-NR1S896 or anti-NR1 antibodies. Data are presented as mean±SE (**p<0.01 Student’s t-test. N=8-20 for each group).
(A) Phospho-NR1S896 levels in mania related animal models..
(B) Total NR-1 levels in mania related animal models..