TABLE 3. Multivariate Cox Proportional Hazards Model.
Variable | Outcome | Hazards Ratio | 95% CI | P |
---|---|---|---|---|
PSA >100 ng/mL | PSA failure | 1.05 | 0.69-1.60 | .181 |
Metastases | 0.97 | 0.49-1.90 | .918 | |
Cancer survival | 0.87 | 0.37-2.06 | .749 | |
Gleason score | PSA failure | 1.14 | 0.97-1.33 | .111 |
Metastases | 1.04 | 0.79-1.38 | .763 | |
Cancer survival | 1.28 | 0.90-1.83 | .168 | |
Organ confined | PSA failure | 0.58 | 0.31-1.08 | .085 |
Metastases | 0.32 | 0.06-1.75 | .192 | |
Cancer survival | 0.79 | 0.07-9.43 | .854 | |
Seminal vesicle invasion | PSA failure | 1.25 | 0.77-2.03 | .368 |
Metastases | 2.27 | 0.88-5.82 | .089 | |
Cancer survival | 3.26 | 0.76-14.07 | .113 | |
Positive margins | PSA failure | 1.04 | 0.68-1.59 | .856 |
Metastases | 1.09 | 0.51-2.31 | .833 | |
Cancer survival | 2.57 | 0.73-9.02 | .141 | |
Positive lymph nodes | PSA failure | 1.06 | 0.64-1.78 | .812 |
Metastases | 1.37 | 0.62-3.05 | .440 | |
Cancer survival | 3.20 | 1.06-9.62 | .039 | |
Adjuvant ADT | PSA failure | 0.24 | 0.14-0.40 | <.001 |
Metastases | 0.60 | 0.25-1.42 | .243 | |
Cancer survival | 0.62 | 0.16-2.32 | .473 | |
Adjuvant EBRT | PSA failure | 0.41 | 0.23-0.72 | .002 |
Metastases | 0.55 | 0.22-1.35 | .190 | |
Cancer survival | 0.61 | 0.22-1.73 | .345 |
95% CI indicates 95% confidence interval; PSA, prostate-specific antigen; ADT, androgen deprivation therapy; EBRT, external beam radiotherapy.