Table 1.
Mean cardiovascular disease risk factor levels by time period among participants with and without diabetes in the Framingham Heart Study (1970–2005).
| Time Period | ||||||||
|---|---|---|---|---|---|---|---|---|
| 1970–79 | 1980–89 | 1990–99 | 2000–05 | |||||
| Age 50 | N | % | N | % | N | % | N | % |
| Women | ||||||||
| No Diabetes | 420 | 49.5 | 657 | 50.9 | 653 | 54.3 | 350 | 54.1 |
| Diabetes | 13 | 39.4 | 24 | 40.7 | 33 | 42.3 | 16 | 45.7 |
| N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | |
| Age, years | ||||||||
| No Diabetes | 848 | 50.2 (1.4) | 1292 | 49.9 (1.3) | 1203 | 49.8 (1.1) | 647 | 49.7 (1.4) |
| Diabetes | 33 | 50.5 (1.5) | 59 | 50.1 (1.3) | 78 | 50.1 (1.2) | 35 | 50.2 (1.4) |
| Body mass index, kg/m2 | ||||||||
| No Diabetes | 845 | 26.4 (3.8) | 1288 | 26.6 (4.5) | 1198 | 27.4 (5.0) | 647 | 27.2 (5.2) |
| Diabetes | 33 | 28.3 (4.6) | 59 | 30.6 (5.9) | 78 | 33.3 (6.4) | 34 | 35.7 (8.0) |
| Total cholesterol, mg/dL | ||||||||
| No Diabetes | 785 | 220 (38) | 1268 | 216 (37) | 1198 | 202 (36) | 645 | 200 (36) |
| Diabetes | 30 | 242 (58) | 56 | 224 (54) | 77 | 207 (40) | 35 | 187 (36) |
| LDL cholesterol, mg/dL | ||||||||
| No Diabetes | 781 | 141 (36) | 1218 | 139 (35) | 1177 | 125 (33) | 631 | 119 (33) |
| Diabetes | 30 | 161 (60) | 51 | 140 (46) | 65 | 128 (30) | 35 | 111 (32) |
| Systolic blood pressure, mm Hg | ||||||||
| No Diabetes | 845 | 130 (18) | 1292 | 125 (16) | 1203 | 121 (16) | 647 | 121 (15) |
| Diabetes | 33 | 141 (22) | 59 | 132 (16) | 78 | 134 (19) | 35 | 129 (16) |
| Diastolic blood pressure, mm Hg | ||||||||
| No Diabetes | 845 | 83 (11) | 1292 | 81 (9) | 1203 | 76 (10) | 647 | 77 (9) |
| Diabetes | 33 | 86 (12) | 59 | 84 (10) | 78 | 82 (10) | 35 | 78 (11) |
| Age 60 | N | % | N | % | N | % | N | % |
| Women | ||||||||
| No Diabetes | 530 | 56.6 | 464 | 51.2 | 584 | 52.9 | 131 | 56.7 |
| Diabetes | 33 | 51.6 | 31 | 38.8 | 42 | 33.3 | 23 | 48.9 |
| N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | N | Mean (SD) | |
| Age, years | ||||||||
| No Diabetes | 936 | 59.8 (1.4) | 906 | 59.7 (1.2) | 1105 | 59.7 (1.1) | 231 | 59.4 (1.2) |
| Diabetes | 64 | 59.8 (1.4) | 80 | 59.8 (1.3) | 126 | 59.7 (1.1) | 47 | 59.5 (1.2) |
| Body mass index, kg/m2 | ||||||||
| No Diabetes | 932 | 26.4 (4.1) | 899 | 26.6 (4.3) | 1102 | 27.7 (4.7) | 230 | 28.0 (5.0) |
| Diabetes | 63 | 28.1 (4.4) | 79 | 29.7 (5.1) | 124 | 30.7 (5.9) | 43 | 33.8 (7.5) |
| Total cholesterol, mg/dL | ||||||||
| No Diabetes | 487 | 234 (42) | 891 | 224 (40) | 1101 | 209 (39) | 231 | 203 (35) |
| Diabetes | 38 | 233 (61) | 80 | 222 (47) | 123 | 199 (39) | 43 | 189 (37) |
| LDL cholesterol, mg/dL | ||||||||
| No Diabetes | 487 | 152 (40) | 857 | 145 (35) | 1077 | 130 (33) | 229 | 120 (31) |
| Diabetes | 38 | 154 (53) | 73 | 134 (38) | 117 | 122 (36) | 42 | 104 (29) |
| Systolic blood pressure, mm Hg | ||||||||
| No Diabetes | 932 | 138 (20) | 906 | 133 (18) | 1105 | 128 (17) | 231 | 127 (19) |
| Diabetes | 64 | 152 (23) | 80 | 142 (16) | 126 | 137 (21) | 47 | 135 (17) |
| Diastolic blood pressure, mm Hg | ||||||||
| No Diabetes | 932 | 83 (11) | 905 | 81 (9) | 1104 | 76 (9) | 231 | 77 (10) |
| Diabetes | 64 | 85 (14) | 80 | 81 (9) | 126 | 77 (11) | 46 | 79 (9) |
a
Sample size is 4,195 (3,990 non-DM, 205 DM) for age 50 analysis and 3,495 (3,178 non-DM, 317 DM) for age 60 analysis.