Figure 3. Sensitivity to transgenic mice to oxidative stress.
The sensitivity of embryonic fibroblasts isolated from WT, SOD1 Tg, Sod2 Tg, and SOD1/Sod2 Tg mice to paraquat (48 hrs) was determined as previously described [59]. The data are the mean ± SEM of experiments repeated with fibroblasts derived from three animals and were analyzed by two-way ANOVA. Values that are significant different (p< 0.05) from each other are shown with different subscripts.