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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Nov 3;1798(1):59–64. doi: 10.1016/j.bbamem.2009.10.017

Table 1.

Effects of ceramide and/or diacylglycerol in bilayers originally composed of PC: SM: PE: Ch (1: 1: 1: 1, mol ratio). Data are average ±S. D.

Composition Enzyme bindinga K0.5 (µM) Enzyme binding maximum rates b(s−1) PlcHR2 aggregation lag timec (s)
Control 20 ± 2.5 3 ± 1 46 ± 0.5
+10% Cer 3.0 ± 0.325 8 ± 0.5 12 ± 0.5
+10% DAG 1.8 ± 0.01 6 ± 0.5 5 ± 0.2
+5% Cer + 5% DAG 0.72 ± 0.205 7 ± 1 8 ± 0.3
a

Data derived from the experiments in Fig. 2A (n=3).

b

Data derived from the experiments in Fig. 2B (n=3). Maximum rates are also the initial rates when lag time is ≈0.

c

Data derived from the experiments in Fig. 4 (n=3).