Table 1A.

Tumor, Node, Metastases (TNM) Classification of Colorectal Cancer

T-Primary tumor

Tx Primary tumor cannot be assessed

T0 No evidence of primary tumor

Tis Carcinoma in situ: intraepithelial or invasion of lamina propria

T1 Tumor invades submucosa

T2 Tumor invades muscularis propria

T3 Tumor invades through muscularis propria into subserosa or into non-peritonealized pericolic or perirectal tissues

T4 Tumor directly invades other organs or structures and/or perforates visceral peritoneum

N-Regional lymph nodes

NX Regional lymph nodes cannot be assessed

N0 No regional lymph node metastasis

N1 Metastasis in one to three regional lymph nodes

N2 Metastasis in four or more regional lymph nodes

M-Distant metastasis

MX Distant metastasis cannot be assessed

M0 No distant metastasis

M1 Distant metastasis