Top, a: Schematic description of the TE=39ms PRESS with WET water suppression. Localization along X and Y (LR×AP) was ×16 CSI. The ×4 partitions along Z (IS) were achieved by sequentially encoding two slabs each TR=1600 ms, with 2nd order HSI, as shown in 2b, with the 5.12 ms PRESS 90° pulse. The two refocusing 180°s were 12.8 ms long numerically optimized Shinnar-LeRoux pulses under the selective-gradient strengths indicated. Bottom, left, b: The spatial excitation profiles of the two 2nd order HSI slabs in the VOI. The goal was to reduce the B1 demands and the inter-slice “bleed” (Goelman et al.2006b;Goelman et al.2006a). Bottom, right, c: The four slice profiles obtained by the two inverse 2nd order Hadamard transforms, Ĥ2−1, indicated as i±j with i and j indicating the pulse numbers in 2b.