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. Author manuscript; available in PMC: 2009 Dec 7.
Published in final edited form as: Mol Reprod Dev. 2009 Dec;76(12):1116–1127. doi: 10.1002/mrd.21066

Figure 2.

Figure 2

Juxtacrine Functions of HBEGF. Transmembrane proHBEGF is depicted mediating attachment between the trophoblast cell of a blastocyst and the surface of the uterine luminal epithelium. HBEGF can potentially bind HSPG, HER1, or HER4, to both mediate cell adhesion and elicit juxtacrine signaling downstream of HER kinases.