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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Drug Alcohol Depend. 2009 Aug 21;105(1-2):132–138. doi: 10.1016/j.drugalcdep.2009.06.022

Table 1.

Sample description

Modified Intention to Treat Sample (ITT, n=50)

Full ITT Sample (n=59) Modified ITT Buspirone ( n=23) Placebo (n=27)




Domain Variable Mean SD Mean SD p-value {a} Mean SD Mean SD p-value {b}
Demographics
    Age 31.4 9.8 31.6 10.2 0.97 29.5 8.4 33.4 11.3 0.32
    Sex, N (%) male 52 88% 45 90% 0.29 19 83% 26 96% 0.17
    Race, N (%) Caucasian 51 86% 43 86% 1.00 19 83% 24 89% 0.69
Psychiatric Measures
    Hamilton Anxiety Rating Scale 9.1 6.6 9.1 6.9 0.67 10.3 7.1 8.1 6.7 0.24
Substance Use Measures
    Self Efficacy Score 3.2 1.2 3.3 1.2 0.82 3.2 1.2 3.3 1.2 0.55
    Reason for Quiting Score 10.9 6.2 11.0 6.6 0.76 12.1 7.3 10.2 5.8 0.34
    Marijuana Problem Score 8.8 4.4 9.0 4.5 0.25 9.1 4.4 9.0 4.7 0.91
    Marijuana Craving Questionnaire (MCQ)
    MCQ: Compulsion 8.4 4.4 8.3 4.3 0.95 8.3 4.6 8.4 4.1 0.91
    MCQ: Emotion 10.5 4.6 10.2 4.6 0.26 9.5 5.5 10.7 3.8 0.49
    MCQ: Expectancy 13.0 4.4 12.9 4.4 0.84 12.4 4.0 13.3 4.8 0.46
    MCQ: Purposefulness 13.3 5.2 13.2 5.3 0.86 12.5 6.1 13.9 4.5 0.35
    MCQ: Total Score 45.1 14.4 44.6 14.4 0.59 42.6 15.9 46.3 13.1 0.40
    Withdrawal checklist 18.6 10.4 17.9 9.4 0.70 18.6 7.4 17.4 10.9 0.50
Self-reported use based on 90 day time line follow back
    % Days of TLFB with reported use 90% 15% 89% 16% 0.07 87% 20% 91% 11% 0.80
    Amount Using Per Using Day 4.0 2.9 3.8 2.5 0.76 3.3 2.1 4.2 2.7 0.28
{a}

For a comparison for differences in the n=9 participants included in the full ITT sample that were not included in the n=50 modified ITT sample.

{b}

For a comparison of differences between treatment groups in the modified ITT sample.