Table 1.
Sample description
Modified Intention to Treat Sample (ITT, n=50) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Full ITT Sample (n=59) | Modified ITT | Buspirone ( n=23) | Placebo (n=27) | |||||||
Domain Variable | Mean | SD | Mean | SD | p-value {a} | Mean | SD | Mean | SD | p-value {b} |
Demographics | ||||||||||
Age | 31.4 | 9.8 | 31.6 | 10.2 | 0.97 | 29.5 | 8.4 | 33.4 | 11.3 | 0.32 |
Sex, N (%) male | 52 | 88% | 45 | 90% | 0.29 | 19 | 83% | 26 | 96% | 0.17 |
Race, N (%) Caucasian | 51 | 86% | 43 | 86% | 1.00 | 19 | 83% | 24 | 89% | 0.69 |
Psychiatric Measures | ||||||||||
Hamilton Anxiety Rating Scale | 9.1 | 6.6 | 9.1 | 6.9 | 0.67 | 10.3 | 7.1 | 8.1 | 6.7 | 0.24 |
Substance Use Measures | ||||||||||
Self Efficacy Score | 3.2 | 1.2 | 3.3 | 1.2 | 0.82 | 3.2 | 1.2 | 3.3 | 1.2 | 0.55 |
Reason for Quiting Score | 10.9 | 6.2 | 11.0 | 6.6 | 0.76 | 12.1 | 7.3 | 10.2 | 5.8 | 0.34 |
Marijuana Problem Score | 8.8 | 4.4 | 9.0 | 4.5 | 0.25 | 9.1 | 4.4 | 9.0 | 4.7 | 0.91 |
Marijuana Craving Questionnaire (MCQ) | ||||||||||
MCQ: Compulsion | 8.4 | 4.4 | 8.3 | 4.3 | 0.95 | 8.3 | 4.6 | 8.4 | 4.1 | 0.91 |
MCQ: Emotion | 10.5 | 4.6 | 10.2 | 4.6 | 0.26 | 9.5 | 5.5 | 10.7 | 3.8 | 0.49 |
MCQ: Expectancy | 13.0 | 4.4 | 12.9 | 4.4 | 0.84 | 12.4 | 4.0 | 13.3 | 4.8 | 0.46 |
MCQ: Purposefulness | 13.3 | 5.2 | 13.2 | 5.3 | 0.86 | 12.5 | 6.1 | 13.9 | 4.5 | 0.35 |
MCQ: Total Score | 45.1 | 14.4 | 44.6 | 14.4 | 0.59 | 42.6 | 15.9 | 46.3 | 13.1 | 0.40 |
Withdrawal checklist | 18.6 | 10.4 | 17.9 | 9.4 | 0.70 | 18.6 | 7.4 | 17.4 | 10.9 | 0.50 |
Self-reported use based on 90 day time line follow back | ||||||||||
% Days of TLFB with reported use | 90% | 15% | 89% | 16% | 0.07 | 87% | 20% | 91% | 11% | 0.80 |
Amount Using Per Using Day | 4.0 | 2.9 | 3.8 | 2.5 | 0.76 | 3.3 | 2.1 | 4.2 | 2.7 | 0.28 |
For a comparison for differences in the n=9 participants included in the full ITT sample that were not included in the n=50 modified ITT sample.
For a comparison of differences between treatment groups in the modified ITT sample.