Figure 4.

Representative histological sections showing EpCAM expression in tumor-associated stroma related to histological grade. A: Normal area showing no stromal staining. B: Tumor region with low Gleason pattern showing patchy and weak staining in the tumor associated stroma. C: Tumor region with moderate Gleason pattern with perineurial invasion (center of the picture) and extensive EpCAM staining in the stroma. D–F: Tumor region with high Gleason pattern showing more intense tumor associated stromal staining. All images were taken at a magnification of ×20.