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. 2009 Dec;175(6):2309–2318. doi: 10.2353/ajpath.2009.081017

Figure 9.

Figure 9

Analysis of lung caspase 3 expression after treatment with L-NAME. Wild-type (WT) and GGTenu1 mice were pre-treated with L-NAME before exposure to hyperoxia for 48 hours as described in Materials and Methods. L-NAME treatment was associated with a 67% decrease in caspase 3 protein expression by Western blot in GGTenu1 lung exposed to hyperoxia compared with normoxia, and a 50% decline in wild-type lung exposed to hyperoxia compared with normoxia. Tubulin expression was assessed as a loading control.