Figure 4.

Cell-identity analysis of OTX1⁺ cells in the GC of nmLN. Immunohistochemistry experiments to assess at single cell level co-localization between OTX1⁺ cells and those expressing CD45 (A–C), or PAX5 (D–F), or BCL6 (G–I), or CD10 (J–L), or CD20 (M–O), or CD138 (P–R), or IgG (S–U) show that OTX1⁺ cells never co-express PAX5 or BCL6, while several of them co-localize with CD10 and CD20, and all of them are CD45⁺, CD138⁺, and IgG⁺. The arrows point to OTX1⁺ cells co-expressing CD45, or CD10, or CD20, or CD138, or IgG; the arrowheads point to the cells expressing only OTX1.