Fluorescence angiography of CNV lesions. Fundi of Brown Norway rat eyes were photocoagulated and treated with intravitreal injections of ANP or vehicle as control (A). Representative fluorescein angiograms of animals treated with vehicle or ANP. B: The percentage of lesions graded as 0, I, and IIa, defined as no leakage to moderate leakage, and IIb, considered clinically relevant leakage, in vehicle-treated (n = 20) and ANP-treated animals (n = 18); *P < 0.05.