Reconstituted systems containing CPR and DLPC (▼), HO-1 and DLPC (Δ), and HO-1, CPR, and DLPC (■) were preincubated for 2 hrs at room temperature prior to assay. Proteins not included in pre-incubation procedure were added just prior to the initiation of the reaction. The final HO-1 concentration was 0.1 µM, and bilirubin production was monitored at 468nm. Assay details are discussed in “Experimental Procedures.” Values represent the mean +/− S.E. of n=3.