Table 4.
The sensitivity and specificity of EYA4 and hTERT mRNA expression
| ESCC | ESCD | BCH | |||||
|---|---|---|---|---|---|---|---|
| item | Cut off level |
Sensitivity (%) |
Specificity (%) |
Sensitivity (%) |
Specificity (%) |
Sensitivity (%) |
Specificity (%) |
| hTERT | |||||||
| ≥ 0.3 | 96.0 | 5.0 | 98.0 | 5.0 | 98.0 | 5.0 | |
| 0.5- | 88.0 | 19.0 | 93.0.0 | 22.0 | 90.0 | 22.0 | |
| 1.0- | 60.0 | 72.0 | 48.0 | 72.0 | 31.0 | 72.0 | |
| 1.5- | 12.0 | 94.4 | 12.0 | 90.0 | 5.0 | 90.0 | |
| AUC | 0.820 | 0.671 | 0.566 | ||||
| EYA4 | |||||||
| ≥ 0.20 | 76.0 | 64.0 | 36.0 | 64.0 | 12.0 | 64 | |
| 0.30- | 40.0 | 73.0 | 27.0 | 73.0 | 0.0 | 73 | |
| 0.40- | 20.0 | 90.0 | 10.0 | 90.0 | 0.0 | 90 | |
| 0.47- | 16.0 | 100.0 | 4.0 | 100.0 | 0.0 | 100.0 | |
| AUC | 0.693 | 0.553 | 0.520 | ||||
NOTE. AUC:area under curve. The cut-off levels (the band intensity ratios of hTER or EYA4 to β-actin) written in bold are the cut-off points that used in the discriminating between positive and negative status with different markers. BCH, Basal cell hyperplasia; ESCD, esophageal squamous cells dyspalsia; ESCC, esophageal squamous cells cancer.