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Sphingolipid content and DNA fragmentation in the right atrial appendage of lean (white bars, n = 11), overweight/obese (gray bars, n = 11) and overweight/obese type 2 diabetic (black bars, n = 15) patients. Values are means ± SEM. * significant difference versus lean subjects, † significant difference versus overweight/obese patients. S1P, sphingosine-1-phosphate.
