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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: Neurotoxicology. 2009 Sep 6;30(6):898–914. doi: 10.1016/j.neuro.2009.08.011

Table 1.

Number of genes and GO categories in control and lead-treated trans-eQTL transbands. The 5 control (con) and 7 lead-treated (trt) trans-eQTL transbands and their approxiamate cytological locations are indicated in the first column. The second column shows the location of a transband by linkage group and centimorgans (cM) (1 = X chromosome (bands 1–20), 2 = 2L and part of 2R (bands 21–60), 3 = distal 2R (bands 61–80), and 4 (chromosome 3 (bands 81–100). GO, is the most significant gene ontological (GO) category for the genes in the transband. The false discovery rate (FDR) is shown underneath. # permutations with this GO category, is the number of permutations (out of 200) that have a transband with significant GO (FDR ≤ 0.01).

Transbands cM Number
of genes
GO (FDR) # permutations
with this GO
category
con_27B 2_46 117 Cell Cycle
(0.01)
0/200
con_50DF 2_161 152 Alternative
splicing (4.41E-06)
19/200
con_70C 4_136 103 None
con_72A 4_141 134 Hydrolase
(3.87E-04)
17/200
con_73D 4_146 278 Hydrolase
(1.43E-26)
17/200
trt_3E 1_11 245 Developmental
Protein
(5.68E-03)
15/200
trt_30AB 2_71 194 Actin Binding
(4.80 E-04)
0/200
trt_57F 3_6 96 Golgi apparatus
(0.01)
0/200
trt_63A 4_21 140 Mitochondrial part
(0.0022)
14/200
trt_65A 4_31 98 None
trt_73D 4_146 222 Hydrolase
(7.65E-12)
17/200
trt_77E 4_156 103 Carbohydrate
metabolic process
(3.45 E-15)
2/200