. Author manuscript; available in PMC: 2010 Nov 1.

Published in final edited form as: Neurotoxicology. 2009 Sep 6;30(6):898–914. doi: 10.1016/j.neuro.2009.08.011

Table 2.

Polarity of 5 control and 7 treated trans-eQTL transbands. The transband locations are in the first row (see Table 1). Polarity is determined in four manners (first row). For example, (B + Pb/B − Pb) is the ratio of the level of expression of a gene with the B genotype in the presence of lead over the level of expression of the same gene in the absence of lead. The ratio (n>1:n<1), where n>1 is the number of genes in a transband that have a relative increase in expression and n<1 is the number of genes in the same transband that have a relative decrease in expression.

transband	B + Pb/B −Pb (n>1:n<1)	O + Pb/O −Pb (n>1:n<1)	O −Pb/B −Pb (n>1:n<1)	O + Pb/B +Pb (n>1:n<1)
con_27B	(72:45)	(83:34)^*	(71:46)	(34:83)^*
con_50DF	(105:47)^*	(38:114)^*	(118:34)^*	(85:67)
con_70C	(53:50)	(52:51)	(57:46)	(54:49)
con_72A	(105:29)^*	(104:30)^*	(108:26)^*	(110:24)^*
con_73D	(170:108)^*	(170:108)^*	(178:100)^*	(176:102)^*
trt_3E	(89:156)^*	(61:184)^*	(82:163)^*	(60:185)^*
trt_30AB	(124:70)^*	(156:38)^*	(127:67)^*	(162:32)^*
trt_57F	(21:75)^*	(51:45)	(44:52)	(71:25)^*
trt_63A	(75:65)	(32:108)^*	(75:65)	(32:108)^*
trt_65A	(33:65)	(17:81)^*	(10:88)^*	(11:87)^*
trt_73D	(128:94)^*	(125:97)^*	(136:86)^*	(138:84)^*
trt_77E	(63:40)	(62:41)	(63:40)	(61:42)
Total	(1038:844)^*	(951:931)	(1069:813)^*	(994:888)^*

P < 0.001 (chi squared test). Bold text, indicates a significant enrichment in genes in a transband with a relative increase in expression. Red text, indicates a significant enrichment in genes in a transband with a relative decrease in expression.Total, the total number of genes in all 12 transbands that either increase or decrease expression in a column.