Table 5. Nervous system development genes down-regulated by lead.
All 59 genes are down-regulated by the GxE-eQTL hotspot located at 50DF. The permutation LOD scores are shown. <3, NS (Not significant). For 8 of the genes, the LOD score is less than 3 and not significant.
| Gene Name (GO: nervous system development) |
LOD Score | Gene Name (GO: nervous system development) |
LOD Score |
|---|---|---|---|
| ABNORMAL | 4.4 | KUZBANIAN | 3.9 |
| CHEMOSENSORY JUMP 6 | |||
| ALK | <3, NS | LADYBIRD LATE | <3 |
| AMYLOID PROTEIN | 8.2 | LAMIN | <3 |
| PRECURSOR-LIKE | |||
| ANK2 | <3, NS | LEONARDO PROTEIN | 5.1 |
| BEATEN PATH IA | 5.8 | LIM1 | 3.4 |
| BEATEN PATH IIA | 5.3 | LONGITUDINALS | 3.4 |
| LACKING | |||
| BONUS | 4.3 | MASTERMIND | 8.3 |
| BROAD | 5.0 | MINIBRAIN | 4.4 |
| CACOPHONY | 6.0 | MUSCLEBLIND | 6.2 |
| CADHERIN-N | 7.9 | NETRIN-B | 6.4 |
| CHARLATAN | 5.8 | NEUROGLIAN | 6.9 |
| CHOLINE | 7.4 | OCELLILESS | 5.3 |
| ACETYLTRANSFERASE | |||
| CONNECTIN | 9.6 | PHYLLOPOD | 6.4 |
| COUCH POTATO | 5.1 | POINTED | 5.3 |
| CUT | 4.9 | PROTEIN SPLIT ENDS | 4.3 |
| DACHSHUND | 3.9 | PURITY OF ESSENCE | 4.8 |
| DERAILED | 4.9 | RETAINED | 3.6 |
| DICHAETE | 4.2 | RHOGAP-93B | <3, NS |
| DISCS LARGE 1 | 7.4 | RHOGAP-P190 | <3, NS |
| DLIC2 | <3, NS | ROUNDABOUT | 5.2 |
| DUMPY | 5.0 | SCABROUS | 8.2 |
| EMBRYONIC LETHAL, | 7.2 | SCALLOPED | 5.9 |
| ABNORMAL VISION | |||
| FASCICLIN 2 | 6.0 | SCRATCH | 6.7 |
| FRUITLESS | 4.2 | SCRIBBLER | 4.8 |
| G PROTEIN O 47A | 7.1 | STARRY NIGHT | 10.6 |
| G PROTEIN -SUBUNIT 13F | 5.1 | STILL LIFE | 5.0 |
| HOMOTHORAX | 6.0 | TRIO | <3, NS |
| INSULIN-LIKE RECEPTOR | 4.2 | TURTLE | 4.9 |
| KIN OF IRRE | 3.5 | VEIN | 6.3 |
| KRUPPEL | 3.8 |