Table 6.

Candidate genes from 30AB that mediate the behavioral response to lead. We took gene expression data for 122 probesets nearest our behavioral QTL and asked whether or not strain differences in gene expression levels for these, individually, were correlated with the behavioral change induced by lead treatment. There were seven “significant” (e.g. unadjusted for alpha=0.05) correlations. Ggamma30A is represented twice by two different probesets, as indicated by the Affymetrix ID (Affy ID).

Gene name	Correlation coefficient	P value	Protein function
Cks30A (CG3738)	r=−0.266	P=0.03	amino acid phosphorylation, cell cycle regulation, histoblast morphogenesis
Ggamma30A (CG3694) Affy ID 1637526_S_at	r=0.328	P=0.007	signal transduction via G-protein, visual perception
Ggamma30A (CG3694) Affy ID 1628754_S_at	r=0.31	P=0.011	signal transduction via G-protein, visual perception
CG3838	r=0.276	P=0.024	DNA binding
Nckx30C (CG18660)	r=0.309	P=0.011	ion transport: K, Na, Ca; compound eye development
CG9525	r=−0.288	P=0.018	no known function
CG9573	r=−0.328	P=0.007	protein binding