Table 1.
a) calculated on a per case basis | ||||||||||
Methods | OCT | Cyst | Cyto | p-values | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Tumors | n/N | % | n/N | % | n/N | % | OCT : Cyst | OCT : Cyto | Cyst : Cyto | |
CIS (pTis) | 2/3 66.7 | 0/3 0 | 3/3 100 | 0.400 | 1.000 | 0.100 | ||||
pTa-pT1 |
LG HG |
12/12 100 | 8/12 66.7 | 0/10 0 | 0.093 | 0.0001 | 0.002 | |||
6/6 100 | 6/6 100 | 1/3 33.3 | 1.000 | 0.083 | 0.226 | |||||
Superficial (<pT2) | 20/21 95 | 14/21 66.7 | 4/16 25 | 0.044 | 0.0001 | 0.012 | ||||
≥pT2 | 14/15 93.3 | 13/15 86.6 | 11/13 84.6 | 1.000 | 0.583 | 1.000 | ||||
Sensitivity | 34/36 94.4 | 27/36 75 | 17/29 58.6 | 0.022 | 0.005 | 0.160 | ||||
Specificity | 26/32 81.3 | 17/32 53.2 | 24/27 88.9 | 0.017 | 0.488 | 0.003 | ||||
b) calculated on a per lesion basis | ||||||||||
Methods | OCT | Cyst | Cyto | p-values | ||||||
Tumors | n/N | % | n/N | % | n/N | % | OCT : Cyst | OCT : Cyto | Cyst : Cyto | |
CIS (pTis) | 8/9 88.9 | 2/9 22.2 | 8/8 100 | 0.015 | 1.000 | 0.002 | ||||
pTa-pT1 |
LG HG |
17/17 100 | 11/17 64.7 | 0/14 0 | 0.018 | 0.0001 | 0.0001 | |||
9/9 100 | 8/9 88.9 | 4/6 66.7 | 1.000 | 0.143 | 0.525 | |||||
Superficial (<pT2) | 34/35 97 | 21/35 60 | 12/28 42.9 | 0.002 | 0.0001 | 0.040 | ||||
≥pT2 | 17/18 94.4 | 16/18 88.9 | 14/16 87.5 | 1.000 | 0.591 | 1.000 | ||||
Sensitivity | 51/53 96.2 | 37/53 69.8 | 26/44 59.1 | 0.0003 | 0.0001 | 0.271 | ||||
Specificity | 51/57 89.5 | 42/57 73.7 | 45/48 93.8 | 0.030 | 0.436 | 0.007 |
* Cyst: cystoscopy, Cyto: cytology; N: total number, LG: low grade, Superficial: all pTis and pTa-pT1 tumors. Cytology data for 12 cases were unavailable.