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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Urology. 2009 Aug 5;74(6):1351–1357. doi: 10.1016/j.urology.2009.04.090

Table 1.

Diagnostic sensitivities and specificities:

a) calculated on a per case basis
Methods OCT Cyst Cyto p-values
Tumors n/N % n/N % n/N % OCT : Cyst OCT : Cyto Cyst : Cyto
CIS (pTis) 2/3 66.7 0/3 0 3/3 100 0.400 1.000 0.100
pTa-pT1 LG
HG
12/12 100 8/12 66.7 0/10 0 0.093 0.0001 0.002
6/6 100 6/6 100 1/3 33.3 1.000 0.083 0.226
Superficial (<pT2) 20/21 95 14/21 66.7 4/16 25 0.044 0.0001 0.012
≥pT2 14/15 93.3 13/15 86.6 11/13 84.6 1.000 0.583 1.000
Sensitivity 34/36 94.4 27/36 75 17/29 58.6 0.022 0.005 0.160
Specificity 26/32 81.3 17/32 53.2 24/27 88.9 0.017 0.488 0.003
b) calculated on a per lesion basis
Methods OCT Cyst Cyto p-values
Tumors n/N % n/N % n/N % OCT : Cyst OCT : Cyto Cyst : Cyto
CIS (pTis) 8/9 88.9 2/9 22.2 8/8 100 0.015 1.000 0.002
pTa-pT1 LG
HG
17/17 100 11/17 64.7 0/14 0 0.018 0.0001 0.0001
9/9 100 8/9 88.9 4/6 66.7 1.000 0.143 0.525
Superficial (<pT2) 34/35 97 21/35 60 12/28 42.9 0.002 0.0001 0.040
≥pT2 17/18 94.4 16/18 88.9 14/16 87.5 1.000 0.591 1.000
Sensitivity 51/53 96.2 37/53 69.8 26/44 59.1 0.0003 0.0001 0.271
Specificity 51/57 89.5 42/57 73.7 45/48 93.8 0.030 0.436 0.007

* Cyst: cystoscopy, Cyto: cytology; N: total number, LG: low grade, Superficial: all pTis and pTa-pT1 tumors. Cytology data for 12 cases were unavailable.