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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: Alcohol Clin Exp Res. 2009 Sep 9;33(12):2077–2087. doi: 10.1111/j.1530-0277.2009.01047.x

Figure 2. The effect of chronic ethanol exposure and withdrawal on 5α-reductase-1 activity in (A) hippocampus, (B) cortex, (C) amygdala, (D) midbrain, and (E) adrenals from WSP and WSR mice.

Figure 2

Microsomal fractions from dissected tissues were incubated with a saturating concentration of [3H]progesterone. The amount of [3H]DHP formed was the index of 5α-reductase activity. Values represent the mean ± SEM for the number of animals in parentheses. Data were combined for the two replicates per line at each time point. +P ≤ 0.10, *P ≤ 0.05, **P ≤ 0.01 vs. respective air control, Tukey’s post-hoc test &P < 0.05, &&&P = 0.001 vs. respective WSP, t-test