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. Author manuscript; available in PMC: 2011 Jan 15.
Published in final edited form as: Int J Pharm. 2009 Sep 25;384(1-2):15–23. doi: 10.1016/j.ijpharm.2009.09.033

Figure 2. Time-dependent accumulation of mitoxantrone or BODIPY FL prazosin in BeWo cells.

Figure 2

Accumulation of 20 nM [3H]-mitoxantrone (4 Ci/mmol) or 500 nM BODIPY FL prazosin was measured at 37°C as a function of time, in the absence or presence of the BCRP-specific inhibitor fumitremorgin C (FTC). Each experiment was repeated in triplicate with each point and bar in an individual experiment representing the mean ± S.E.M.. * indicates p < 0.05.