. 2009 Nov 20;10(10):4375–4417. doi: 10.3390/ijms10104375

Table 5.

Regulation of the molecular cascade in the area of turbulent flow.

Graft Material	Location	Biological Response in anastomosis site			Reference
Graft Material	Location	Methodology	Up-Regulated Biomarkers	Down-Regulated Biomarkers	Reference
PTFE	Carotid artery (Dog)	Microarray, RT-PCR and immunohistochemistry.	(α1) collagen -I, (α2) collagen-I, 80K-L protein (MARCKS), osteopontin, NAP-22, VESPR.	Smoothelin-B, tropomyosin 2 (β), calcium/calmodulin-dependent protein kinase II, RBP-MS types 4 and 5, cysteinerich motor neuron 1	[200]
PTFE	Aorta (monkey)	Immunohistochemistry	Osteoblast-specific factor-2 (OSF2)/Cbfα1, (α2)collagen-I, (α1)collagen-III, versican, (α3)collagen-VI, (α2)collagen-V, (α1) collagen-V.	SPARClike-1 (SPARCL1)/hevin, RGS5.	[201]