. Author manuscript; available in PMC: 2010 Sep 1.

Published in final edited form as: Curr Fungal Infect Rep. 2009 Sep 1;3(3):163–169. doi: 10.1007/s12281-009-0021-y

Table 1.

Transcriptional regulators of antifungal resistance.

Transcription factors	Target genes	Binding site	Hyperactive alleles	Reference
Upc2p	ERG genes CDR1, MDR1, YOR1	ARE: TCGTATA(13)- AATATCG	G648D	[18,⁵⁴*]
Tac1p	CDR1, CDR2 PDR16	DRE: CGG(4)CGG	N977D, N972D, G980E, A736V, T225A	[29*,³³]
Mrr1p	MDR1	-	K335N, Q350L, T360I, T381I, P683S, N803D, P683H, R873T, G878E, A880E W893R, T896I, G997V,L998F	[30*,³¹,⁵⁵*]