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Red and green colors indicate the distribution of MBK-2 during the oocyte-to-embryo transition. MBK-2 goes from cortically-enriched to cytoplasmic during the transition (Stitzel et al., 2006) and from inactive (red) to active (green). Under each stage, we indicate 1) the pattern of P-MEI-1 observed in wild-type and in the indicated genotypes, and 2) the proposed primary mode of MBK-2 regulation for that stage.
