Convergence measure of the UNRES energy distributions for the REM (diamonds), SREM (squares), and canonical MD (triangles) simulations of 1E0L, at temperature (a) 220 K and (b) 350 K (with the temperature-independent force field),22 as a function of the simulation time. The χ2 curves are plotted by using the converged UNRES energy distributions from the REM run for 24,000,000 steps as the reference.