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. Author manuscript; available in PMC: 2010 Nov 1.
Published in final edited form as: J Autoimmun. 2009 Oct 9;33(3-4):183–189. doi: 10.1016/j.jaut.2009.09.001

Table 1.

Increased risk of thyroiditis in NOD.H2h4 mice after different environmental exposures

Housing Treatment Odds Ratio
SPF Bromine 1.5
Conventional Bromine 3.89
Conventional LPS 3.9
Conventional Methylcholanthrene 5.67
SPF Iodine 6.67
Conventional Iodine 15.3

LPS 20 ug Salmonella enteriditis given twice i.p. at weekly intervals

Bromine 100 mg/l ( 0.01%)water for 16 weeks

Iodine 0.05% NaI in water for 16 weeks

Methylcholanthrene 0.003g/100 g of chow for 16 weeks

SPF Specific Pathogen Free housing

Odds Ratio over untreated controls calculated according to the formula in Sigma Stat™.