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. Author manuscript; available in PMC: 2010 Nov 12.
Published in final edited form as: Neuron. 2009 Nov 12;64(3):367–380. doi: 10.1016/j.neuron.2009.09.043

Figure 4.

Figure 4

The N termini of both murine CplxI and Drosophila Cplx facilitate neurotransmitter release. (A) Representative traces of evoked EPSCs. The arrows represent stimulations; artifacts and action potentials are blanked. (B) Representative traces of mEPSCs. (C to F) Summary data for Cplx-TKO neurons and Cplx-TKO neurons rescued with different Cplx variants. (C) Vesicular release probability (Pvr) of evoked release. (D) Paired-pulse ratio at 20 ms inter-stimulus interval (ISI). (E) EPSC amplitude potentiation by elevation of external Ca2+ concentrations. (F) mEPSC frequency. Data are expressed as mean ± SEM. *, P < 0.05; ***; P < 0.0001 compared to Cplx-TKO neurons. The numbers of neurons analyzed are shown above the bars.