Figure 2.
(A) Plot of relative mating efficiency vs. surface area of the P2 side chain. Total solvent-accessible side chain surface areas for all residues except Gly were as described by Creighton (39). For Gly, total solvent-accessible side chain surface was estimated as half the surface area of a hydrogen atom. (B) Plot of relative mating efficiency vs. accessible nonpolar surface area. Total solvent-accessible nonpolar side chain surface areas for all residues except Gly were as described by Creighton (39). For Gly, total solvent accessible nonpolar side chain surface was estimated as one-half the surface area of a hydrogen atom.