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. 2009 Sep 29;18(24):4897–4904. doi: 10.1093/hmg/ddp459

Table 3.

Gender effects on allelic association of FOXO1A and FOXO3A with longevity trait in Population 1

SNP Male
Female
MAF (case/control) OR (95% CI) P bP MAF (case/control) OR (95% CI) P bP
rs17630266 0.357/0.360 0.99(0.77–1.27) 0.914 0.91 0.402/0.392 1.04(0.86–1.27) 0.680 0.680
rs2755209 0.245/0.281 0.83(0.63–1.09) 0.166 0.33 0.243/0.294 0.77(0.62–0.95) 0.014 0.028
rs2755213 0.371/0.423 0.80(0.63–1.03) 0.073 0.22 0.348/0.413 0.76(0.62–0.92) 0.005 0.020
rs2253310 0.327/0.248 1.47(1.13–1.90) 0.003 0.014 0.296/0.235 1.37(1.10–1.71) 0.004 0.022
rs2802292 0.328/0.242 1.53(1.17–1.98) 0.001 0.006 0.295/0.236 1.36(1.09–1.69) 0.005 0.016
rs4946936 0.298/0.225 1.46(1.11–1.91) 0.004 0.017 0.280/0.212 1.44(1.15–1.82) 0.001 0.008

MAF, minor allele frequency; OR (95% CI), odds ratio with 95% confidence interval; P, P-value from χ2 test; bP, corrected P by Bonferroni step-down method.