Table 4.
Validation of allelic association of FOXO1A with female longevity in Chinese populations
| SNP | Population 1 |
Population 2 |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MAF (case/control) | PHWT | OR (95% CI) | P | aP | MAF (case/control) | PHWT | OR (95% CI) | P | aP | |
| rs17630266 | 0.402/0.392 | 0.81 | 1.04(0.86–1.27) | 0.680 | 0.838 | 0.407/0.376 | 0.20 | 1.14(0.91–1.42) | 0.240 | 0.203 |
| rs2755209 | 0.243/0.294 | 0.32 | 0.77(0.62–0.95) | 0.014 | 0.011 | 0.220/0.268 | 0.80 | 0.77(0.60–0.99) | 0.039 | 0.025 |
| rs2755213 | 0.348/0.413 | 0.84 | 0.76(0.62–0.92) | 0.005 | 0.003 | 0.324/0.389 | 0.97 | 0.75(0.60–0.94) | 0.011 | 0.009 |
MAF, minor allele frequency; PHWT, P-value from Hardy–Weinberg equilibrium test; OR (95% CI), odds ratio with 95% confidence interval; P, P-value from χ2 test; aP, adjusted P for BMI.