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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Cell Metab. 2009 Oct;10(4):296–308. doi: 10.1016/j.cmet.2009.08.010

Figure 2. Effect of LKB1 Deficiency on Glucose Physiology.

Figure 2

(A) Fed and fasting blood glucose levels (left) and glucose tolerance (right) in LKB1lox/lox and PLKB mice (n = 11 mice per genotype). Mice were injected with tamoxifen at 4 weeks of age, and assays were performed 1 week later.

(B) Insulin sensitivity in LKB1lox/lox and PLKB mice (n = 9 mice per genotype). Same mice were used as in (A).

(C) Serum insulin levels 15 min after the injection of glucose to LKB1lox/lox and PLKB mice (n = 7 mice per genotype). Mice were injected with tamoxifen at 4 weeks of age, and assay was performed 1 month later. Error bars represent standard deviations. **p < 0.01.