Table 14.
Bone marrow micronucleus test of AstraZeneca compound C in female rats
Oral dose (mg/kg) | MNPCE/1000 PCE |
---|---|
0 (vehicle control) | 1.1 |
25 | 2.0a |
76 | 1.7 |
380 | 1.2 |
Results 24 h after dosing (2000 PCEs scored). PCE: polychromatic erythrocyte; MNPCE: micronucleated PCE.
p < 0.05.