Table 3.
Effects of treatment with Tridax procumbens extract on body weight in normal and alloxan diabetic rats.
| Group (n = 6) |
Dose (mg/kg b.wt) |
BODY WEIGHT IN GRAMS | |||||
|---|---|---|---|---|---|---|---|
| Alloxanα) dosing | DAYS AFTER DOSING | ||||||
| 0 dβ) | 7 d | 15 d | 21 d | 30 dγ) | |||
| Normal Control | - | 162.6 ± 4.2a | 201.3 ± 1.9 b (23.80) | 208.4 ± 2.1b (3.52) | 217.4 ± 6.2b (4.31) | 225.8 ± 4.9c (3.86) | 234.4 ± 7.8 c (3.80) |
| Normal+ Extract | 250 | 160.0 ± 3.6a | 196.2 ± 2.7 b (22.62) | 205.5 ± 1.9 b (4.74) | 213.2 ± 5.4 c (3.74) | 221.1 ± 3.2 c (3.70) | 228.6 ± 4.2 c (3.39) |
| Normal+ Extract | 500 | 156.1 ± 2.4a | 197.6 ± 2.1 b (26.58) | 205.1 ± 3.0 b (3.79) | 210.4 ± 4.3 b (2.58) | 218.3 ± 3.7b (3.75) | 227.3 ± 2.9c (4.12) |
| Diabetic Control | - | 156.0 ± 2.9a | 163.4 ± 2.8b (4.74) | 160.4 ± 3.2b -(1.83) | 155.4 ± 4.0 c -(3.11) | 154.6 ± 5.2b -(0.51) | 145.6 ± 5.2c -(5.82) |
| Diabetic+ Extract | 250 | 157.0 ± 3.1a | 164.2 ± 1.7b (4.58) | 165.4 ± 1.9b (0.73) | 167.7 ± 2.8b (1.39) | 176.3 ± 3.2b (5.12) | 182.6 ± 5.0c (3.57) |
| Diabetic+ Extract | 500 | 162.9 ± 2.2a | 171.2 ± 1.4b (5.09) | 173.3 ± 2.1b (1.22) | 176.5 ± 3.1b (1.84) | 183.1 ± 2.5b (3.73) | 189.2 ± 6.4c (3.33) |
| Diabetic+ Glibenc-lamide | 10 | 157.3 ± 1.9a | 165.3 ± 2.4b (5.08) | 167.3 ± 3.0b (1.20) | 168.2 ± 2.8b (0.53) | 174.0 ± 8.7b (2.83) | 176.7 ± 3.8b (1.55) |
Values represent mean ± SEM (n = 6).
*Values for a given group in a row followed by same letter as superscript are not significantly different according to Tukey's multiple comparison procedure (at P < 0.05).
α) At alloxan dosing; β) at initial dosing after fasting (15 d after alloxan dosing); γ) at sacrifice after fasting
Values given in parenthesis are percent (%) body weight change compared to previous observation of their respective group