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. 2009 May 20;117(10):1514–1519. doi: 10.1289/ehp.0800359

Table 1.

Serum concentration of selected organochlorine insecticide compounds and risk of TGCTs.

Lipid-adjusted analyte concentration (ng/g lipid)
ORs for concentration tertiles (reference group: tertile 1)
Cases (n = 49)
Controls (n = 51)
Tertile 1 Tertile 2
Tertile 3
Analyte Median (range) Median (range) pWilcoxona nCo/nCa nCo/nCa OR (95% CI)b nCo/nCa OR (95% CI)
DDT metabolite
o,p′-DDT 20.7 (6.0–220.5) 16.6 (0.3–171.9) 0.36 17/16 17/11 0.8 (0.2–2.6) 17/21 1.4 (0.4–4.5)
p,p′-DDT 226.0 (92.2–584.1) 194.6 (29.3–661.0) 0.23 17/11 17/20 2.3 (0.7–7.2) 17/18 2.1 (0.6–7.2)
p,p′-DDE 2098.5 (750.0–9512.2) 1833.2 (224.9–7436.3) 0.07 17/11 17/18 1.8 (0.6–5.5) 17/20 2.2 (0.7–6.5)

Chlordane
 Heptachlor epoxide 12.0 (0.1–43.6) 11.9 (0.2–27.4) 0.18 16/12 16/16 1.7 (0.5–5.8) 16/20 2.4 (0.6–9.1)
 Oxychlordane 13.4 (0.6–77.4) 11.8 (0.8–79.4) 0.05 16/11 15/20 3.0 (0.8–11.1) 15/18 3.2 (0.6–16.8)
trans-Nonachlor 23.2 (10.7–76.9) 20.5 (8.3–99.2) 0.07 17/10 17/21 3.1 (0.8–11.6) 17/18 2.6 (0.7–8.9)
 Total 47.3 (17.9–143.2) 45.2 (19.0–206.0) 0.048 17/13 17/17 1.8 (0.5–6.5) 17/19 2.3 (0.6–7.2)

Other insecticide
 β-HCH 143.0 (58.4–414.0) 129.7 (59.7–295.9) 0.20 17/15 17/13 1.0 (0.4–2.7) 17/21 1.8 (0.5–6.1)
 Dieldrin 54.2 (0.6–177.9) 54.7 (0.7–251.0) 0.46 17/11 17/22 3.3 (0.8–12.7) 17/15 2.1 (0.5–9.5)
 γ-HCH 6.4 (0.1–42.4) 6.8 (0.2–45.1) 0.89 17/17 17/15 1.0 (0.3–3.1) 17/17 1.1 (0.2–5.0)
 HCB 713.4 (199.5–2458.2) 568.6 (168.6–3185.9) 0.26 17/15 17/13 1.1 (0.3–3.7) 17/21 2.9 (0.5–15.2)
 Mirex 1.7 (0.1–26.0) 1.5 (0.1–14.9) 0.10 17/16 16/13 0.9 (0.3–2.9) 16/17 1.2 (0.4–3.0)

Abbreviations: nCa, number of cases; nCo, number of controls.

a

p-Value from Wilcoxon signed-rank test of matched case–control sets.

b

ORs and 95% CIs calculated from conditional logistic regression of matched case–control sets.