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. Author manuscript; available in PMC: 2010 Nov 10.
Published in final edited form as: Eur J Pharmacol. 2009 Sep 14;622(1-3):15–24. doi: 10.1016/j.ejphar.2009.09.001

Fig. 4.

Fig. 4

EB does not affect the cannabinoid-induced presynaptic inhibition of GABAergic synaptic input onto POMC neurons. Membrane current tracings show the spontaneous mIPSCs recorded in a control cell (A) and EB-treated cell (B) at baseline (left) and following exposure to 1 μM WIN 55,212-2 (middle). On the right are the cumulative probability plots illustrating the comparable increase in interval between contiguous mIPSCs. C, Composite bar graph illustrating the decrease in mIPSC frequency produced by WIN 55,212-2 in arcuate neurons from ethanol vehicle-treated and EB-treated slices (n=4–5). Bars represent means and vertical lines 1 S.E.M. of the mIPSC frequency seen with 1 μM WIN 55,212-2 that were normalized to their respective control values.