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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2009 Jul 18;1802(1):11–19. doi: 10.1016/j.bbadis.2009.07.007

Figure 1. Mitochondrial targeting signals in alpha synuclein and APP proteins.

Figure 1

Figure 1

A, Physico-chemical similarities of N-terminal 32 aminoacid sequence of human alpha synuclein with mitochondrial targeting signals of human P40Scc and P450 c27. (B) Comparison of N-terminal chimeric signals of P450 1A1, 2B1, 2E1 and 2D6 with N-terminus of APP comprising of hydrophobic ER-targeting domain followed by the positively charged mitochondrial-targeting domain.