Table 7.
Estimates of Odds Ratios and p Values of Trend Tests for Rheumatoid Arthritis and Type 1 Diabetes in the WTCCC Data
RA |
T1D |
||||||
---|---|---|---|---|---|---|---|
Chr | SNP | Est | SE | p Value | Est | SE | p Value |
1p13 | rs6679677 | 1.95 | 0.124 | 8.9 × 10−26 | 1.89 | 0.117 | 5.1 × 10−25 |
6(RA) | rs6457617 | 0.44 | 0.020 | 5.5 × 10−72 | 0.71 | 0.031 | 2.3 × 10−15 |
6(T1D) | rs9272346 | 0.72 | 0.032 | 4.7 × 10−14 | 0.27 | 0.015 | 9.1 × 10−122 |
7q32 | rs11761231 | 0.81 | 0.036 | 2.4 × 10−6 | 0.91 | 0.039 | 2.8 × 10−2 |
10p15 | rs2104286 | 0.80 | 0.039 | 7.1 × 10−6 | 0.81 | 0.038 | 1.1 × 10−5 |
12q13 | rs11171739 | 0.99 | 0.042 | 8.6 × 10−1 | 1.33 | 0.055 | 1.3 × 10−11 |
12q24 | rs17696736 | 1.13 | 0.048 | 3.5 × 10−3 | 1.39 | 0.058 | 3.4 × 10−15 |
16p13 | rs12708716 | 0.97 | 0.043 | 4.5 × 10−1 | 0.79 | 0.035 | 7.4 × 10−8 |
The following abbreviations are used: RA, rheumatoid arthritis; T1D, type 1 diabetes; Est, estimate of odds ratio; SE, standard error estimate. p values shown are p values of trend test.