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. 2009 Dec 11;85(6):775–785. doi: 10.1016/j.ajhg.2009.10.016

Figure 4.

Figure 4

Q-Q Plots of the p Values from the Simulated Association Analyses with or without Correction for Population Stratification

The columns correspond to the Q-Q plots of the uncorrected, GC-corrected, and PCA-corrected p values. The rows correspond to 20%, 40%, 80%, and 100% stratification of the simulated case and control samples.

(A–C) 20% stratification: 500N cases, 400N and 100S controls.

(D–F) 40% stratification: 500N cases, 300N and 200S controls.

(G–I) 80% stratification: 500N cases, 100N and 400S controls.

(J–L) 100% stratification: 500N cases and 500S controls.