Figure 5. Influence of NPT compounds on resuscitation of M. tuberculosis “non-culturable” cells obtained in vitro.

“Non-culturable” cells of M. tuberculosis cultures were obtained after cell cultivation during 50 days in Sauton's medium without K⁺. Resuscitation was performed in the absence or presence of inhibitors at 10 µg/ml using 10-fold serial dilutions (MPN assay). MPN values were counted periodically during resuscitation time until their stabilization.