Table 3.

Amelioration of disease severity in animal models by SD0006

	Improvement relative to control
Rat carageenan paw(30 mpk)	67% pain
	58% paw swelling
Rat SCW arthritis	95.1% at 60 mg/kg
	43.7% at 2 mg/kg
Mouse CIA	16% incidence at
	15 mg/kg b.i.d. vs. 89% in
	vehicle control