Table 1.
Correlation with pCR (univariate logistic regression analysis)
| n | events | % pCR | OR | 95% CI | p | |
|---|---|---|---|---|---|---|
| age (per year) | 116 | 13 | - | 0.96 | 0.90-1.01 | 0.128 |
| biology-based tumor type | 116 | 13 | 0.044a | |||
| HR+/HER2- | 57 | 1 | 1.8 | 1.00 | ||
| HR+/HER2+ | 13 | 3 | 23.1 | 16.80 | 1.59-178.12 | 0.019 |
| HR-/HER2+ | 13 | 1 | 7.7 | 4.67 | 0.27-79.96 | 0.288 |
| HR-/HER2- | 33 | 8 | 24.2 | 17.92 | 2.13-151.04 | 0.008 |
| Ki67 | 106 | 12 | ||||
| <= 20% | 85 | 5 | 5.9 | 1.00 | ||
| > 20% | 21 | 7 | 33.3 | 8.00 | 2.22-28.79 | 0.001 |
| CK5/6 | 114 | 13 | ||||
| negative | 107 | 10 | 9.3 | 1.00 | ||
| positive | 7 | 3 | 42.9 | 7.28 | 1.42-37.22 | 0.017 |
| COX-2 | 101 | 12 | ||||
| negative | 27 | 5 | 18.5 | 1.00 | ||
| positive | 74 | 7 | 9.5 | 0.46 | 0.13-1.60 | 0.221 |
| YB-1 | 106 | 12 | ||||
| negative | 71 | 8 | 11.3 | 1.00 | ||
| positive | 35 | 4 | 11.4 | 1.02 | 0.28-3.36 | 0.980 |
| therapy arm | 116 | 13 | ||||
| ddADOC | 61 | 3 | 4.9 | 1.00 | ||
| AC-DOC | 55 | 10 | 18.2 | 4.30 | 1.12-16.53 | 0.034 |
| histology | 116 | 13 | 0.767a | |||
| ductal-invasive | 98 | 12 | 12.2 | 1.00 | ||
| lobular | 14 | 0 | 0.0 | 0.00 | 0.00- - | 0.999 |
| others | 4 | 1 | 25.0 | 2.39 | 0.23-24.86 | 0.466 |
| grade | 116 | 13 | ||||
| G1-2 | 76 | 3 | 3.9 | 1.00 | ||
| G3 | 40 | 10 | 25.0 | 8.11 | 2.09-31.55 | 0.003 |
| cT | 116 | 27 | 0.570a | |||
| cT1 | 9 | 2 | 22.2 | 1.00 | ||
| cT2 | 87 | 9 | 10.3 | 0.40 | 0.07-2.25 | 0.300 |
| cT3 | 20 | 2 | 10.0 | 0.39 | 0.05-3.32 | 0.388 |
| cN | 116 | 27 | ||||
| cN0 | 79 | 8 | 10.1 | 1.00 | ||
| cN1-2 | 37 | 5 | 13.5 | 1.39 | 0.42-4.57 | 0.591 |
OR: odds ratio; CI: confidence interval; a: overall significance.