Table 2.
Microsatellite markers used for loss of heterozygosity analysis
| Microsatellite markers |
Chromosomal region |
Tumor suppressor gene | Function |
|---|---|---|---|
| D3S1255 | 3p24.2-25 | unknown | |
| D9S171 | 9p21 | P16 (INK4A) | Regulator of cell cycle |
| D10S1765 | 10q23.3 | PTEN phosphatase and tensin homologue |
Regulator of cell growth, metabolism and survival |
| D13S218 | 13q12-13 | BRCA2 Breast cancer type 2 |
Regulator of cell cycle |
| D16S421 | 16q22-23 | E-cadherin | Epithelial cell adhesion molecule |
| D17S855 | 17q21 | BRCA1 Breast cancer type 2 |
Regulator of cell cycle |