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. Author manuscript; available in PMC: 2009 Dec 9.
Published in final edited form as: Nat Clin Pract Rheumatol. 2009 Feb;5(2):83–91. doi: 10.1038/ncprheum0987

Table 1.

Genes/SNPs associated with PsA. Numbers of cases/controls used for each study along with corresponding odds ratios (ORs) and P values are shown.

Gene Chs SNP Case Control OR P Ref
IL12B 5q33 rs6887695 576 480 1.1 0.0013 60
748 937 1.5 4.72 × 10−7 133
rs3212227 748 937 1.48 2.1 × 10−5 133
IL23R 1p31 rs11209026 576 480 1.70 8 × 10−4 60
748 937 1.59 0.002 133
IL2/IL21 4q27 rs13151961 576 480 1.37 0.002 60
IL-1 gene cluster 2q13 rs3811047 212 159 1.82 127
TNF-alpha 6p21 −857 375 376 1.96 0.0025 67
HLA class I6p21 rs10484554 576 480 2.4 6.9 × 10−11 60
6p21 HLA-Cw6 94 48
HLA class I - HCP5 6p21 rs2395029 576 480 3.2 1.9 × 10−10 60
Killer inhibitory receptor (2DS1 and/or 2DS2) + HLA-Cw ligand group homozygosity 19q/6p21 366/75 P < 0.0001 6870
HHS Vulnerability Disclosure